Publications

Comparative Computational Modeling of the Bat and Human Immune Response to Viral Infection with the Comparative BiologyImmune Agent Based Model.

authors:

Cockrell, C.; An, G.

Advancing therapies for viral infections using mechanistic computational models of the dynamic interplay between the virus and host immune response.

authors:

Veronika I Zarnitsyna, Juliano Ferrari Gianlupi, Amit Hagar, TJ Sego, James A Glazier.

Generation of multicellular spatiotemporal models of population dynamics from ordinary differential equations, with applications in viral infection

authors:

Sego TJ, Aponte-Serrano JO, Gianlupi JF, Glazier JA.

A multiscale multicellular spatiotemporal model of local influenza infection and immune response.

authors:

Sego TJ, Mochan ED, Ermentrout GB, Glazier JA.

Multiscale Model of Antiviral Timing, Potency, and Heterogeneity Effects on an Epithelial Tissue Patch Infected by SARS-CoV-2.

authors:

Ferrari Gianlupi, J.; Mapder, T.; Sego, T.J.; Sluka, J.P.; Quinney, S.K.; Craig, M.; Stratford, R.E., Jr.; Glazier, J.A.

Model Integration in Computational Biology: The Role of Reproducibility, Credibility and Utility.

authors:

Karr J, Malik-Sheriff RS, Osborne J, Gonzalez-Parra G, Forgoston E, Bowness R, Liu Y, Thompson R, Garira W, Barhak J, Rice J, Torres M, Dobrovolny HM, Tang T, Waites W, Glazier JA, Faeder JR and Kulesza A (2022)

Transcriptogram analysis reveals relationship between viral titer and gene sets responses during Corona-virus infection.

authors:

Rita M C de Almeida, Gilberto L Thomas, James A Glazier

Epidemiological consequences of viral interference: A mathematical modeling study of two interacting viruses.

authors:

Pinky, L., and H.M, Dobrovolny

Specialty Grand Challenge: What it will take to cross the Valley of Death: Translational Systems Biology, “True” Precision Medicine, Medical Digital Twins, Artificial Intelligence and In Silico Clinical trials.

authors:

Gary An

Preparing for the next COVID: Deep Reinforcement Learning trained Artificial Intelligence discovery of multi-modal immunomodulatory control of systemic inflammation in the absence of effective anti-microbials.

authors:

Dale Larie, Gary An, Robert Chase Cockrell