James Sluka

My primary interests are in multiscale modeling of biological systems. My current work at the Biocomplexity Institute includes the development of (1) modeling-language standards (e.g., the Cell Behavior Ontology) and Iinternatiaonl Standards (ISO) , (2) multiscale vascular, liver and epithelial simulations (3) coupling subcellular reaction kinetics and whole body ADME models to multicell models, and (4) drug modeling such as toxicity and bioavailability issues. Currently, I am part of the team developing and maintaining CompuCell3D, a multiscale modeling package. I also have extensive experience in cheminformatics, bioinformatics and software development with emphasis on modeling and text mining tools. I was the lead developer of the Cell Behavior Ontology, which links biological concepts to their instantiation in computer models. I am currently involved in standards development projects and I am a voting member of the International Organization for Standards (ISO) committee on data standards in biotechnology. In 2020 I contributed to a rapid pivot to model development for COVID-19. I am a founding member of an IMAG/MSM working group on modeling for viral pandemics (https://www.imagwiki.nibib.nih.gov/working-groups/multiscale-modeling-and-viral-pandemics).