The initial cohort of project leaders – five early stage investigators from the Departments of Biochemistry, Chemistry, and Chemical and Biomolecular Engineering – are pursuing projects interrelated by their fundamental focus on different aspects of biomolecular communication within and between cells and tissues. These projects are directed toward identifying molecular metabolic signals of microbial syntrophy in the human gut, developing techniques for high-resolution protein glycoform analysis, unraveling ligand-Stabilin-2 interactions in liver disease progression, designing molecular probes for intracellular phosphorylation kinetics, and developing tissue engineering platforms specifically for liver. The breadth of science encompassed by these projects signifies the interdisciplinary nature of the Center’s research goals.
The role of N-glycan carrying Sialyl-Lewis (x) in progression of prostate cancer
Led by Dr. Armen Petrosyan.
Learn MoreIntercellular Communication Between Epithelial Tissues Through Tight Junctions
Led by Dr. Alex Vecchio.
Learn MoreStress-Induced Pathway of Cell-Cell Adhesion Disruption in Pemphigus Pathogenesis
Led by Dr. Ruiguo Yang.
Learn MoreStructure-Mechanism Relationships of a Novel NO-Sensitive Regulator
Led by Dr. Limei Zhang.
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